Webb28 jan. 2024 · Tenascin C (TNC) is a multifunctional large extracellular matrix protein involved in numerous cellular processes in embryonic development and can be increased in disease, or under conditions of trauma or cell stress in adults. However, the role of TNC in lung diseases remains unclear. In this study, we investigated the expression of TNC … WebbTenascin-C (TNC) is a large hexameric extracellular matrix glycoprotein of the tenascin family (PMID: 21818551). It is a multimodular protein containing multiple epidermal growth factor (EGF)-like repeats and fibronectin type III (FN III) domains (PMID: 1719530).
TNC antibody 6 (1 knockout-validated) products in Validated Antibody …
WebbTNC Antibody detects endogenous levels of total TNC. RRID: AB_2841409 Cite Format: Affinity Biosciences Cat# DF8051, RRID:AB_2841409. Conjugate: Unconjugated. Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific). Storage: ... Webb10 aug. 2024 · Interestingly, the results demonstrate that TNC-induced Src activation regulated AR-V7 expression, post-translational stability, and nuclear localization in prostate cancer cells. Treatment with TNC neutralizing antibody, Src knockdown, and inhibition of Src kinase activity repressed AR-V7 transcript and protein. david\u0027s 5 stones
The role of tenascin C in cardiovascular disease - OUP Academic
Webb15 apr. 2024 · TNC was aberrantly upregulated in ligament and entheseal tissues from patients with AS and animal models. TNC inhibition significantly suppressed entheseal new bone formation. Functional assays revealed that TNC promoted new bone formation by enhancing chondrogenic differentiation during endochondral ossification. Webb15 dec. 2009 · TN Alternative names Cytotactin GMEM GP 150-225 Glioma-associated-extracellular matrix antigen Hexabrachion More alternative names Gene names Name TNC Synonyms HXB Organism names Organism Homo sapiens (Human) Taxonomic identifier 9606 NCBI Taxonomic lineage WebbTNC Antibodies (Tenascin C (TNC)) This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric … david\\u0027s 5 stones