Mouse srsf3

Author: gazs

August undefined, 2024

NettetSerine-rich splicing factor 3 (SRSF3) was recently reported as being necessary to preserve RNA stability via an mTOR mechanism in a cardiac mouse model in adulthood. Here, … Nettet18. aug. 2014 · Recently, we demonstrated a role for SRSF3 in controlling hepatocyte differentiation, as well as glucose and lipid metabolism, 19 using a hepatocyte-specific SRSF3 knockout mouse model (SRSF3-HKO). Here, we report that genetic deletion of SRSF3 in hepatocytes causes fibrosis, steatohepatitis, and development of metastatic …

SRSF3 and SRSF7 modulate 3

Nettet3. sep. 2015 · Gene silencing techniques are widely used to control gene expression and have potential for RNAi-based therapeutics. In this report, transgenic mouse lines were created for conditional knockdown... NettetDescription Srsf3 is located on chromosome 17 of mice. Using CRISPR/Cas9 technology, sgRNA and ssDNA are designed, and Srsf3 gene conditional knockout mice are … scph sony

C57BL/6J-Srsf3, Conditional Knockout Mouse (CRISPR/Cas9) …

NettetThese antibodies target SRSF3 in Human, Mouse, Rat and Xenopus laevis samples. Our SRSF3 polyclonal, monoclonal and recombinant monoclonal antibodies are developed … Nettet3. sep. 2015 · only one of four mice with liver/mammary gland expressing Srsf3 siRNA displayed a suppressed level of Srsf3 protein, but not the mRNA. Data indicate that the … http://www.informatics.jax.org/allele/MGI:2669749 scph ps2 bios

SPLICING FACTOR, SERINE/ARGININE-RICH, 3; SRSF3

SRSF3 promotes pluripotency through Nanog mRNA export and

Nettet25. sep. 2024 · Ser/Arg-rich splicing factor 3 (SRSF3) is the smallest member of the SR protein family, and its level is controlled by multiple factors and involves complex mechanisms in eukaryote cells, whereas the aberrant expression of SRSF3 is associated with many human diseases, including cancer. NettetEntry - *603364 - SPLICING FACTOR, SERINE/ARGININE-RICH, 3; SRSF3 - OMIM Gross, M. B. Personal Communication. Baltimore, Md. 8/26/2024. scph stock yahooNettet30. mai 2024 · To investigate the role of SRSF3 in the adult heart, we developed a cardiac-specific tamoxifen-inducible knockout mouse line by crossing SRSF3-floxed and αMHC … scph ps1

"Nettet19. jun. 2024 · Srsf3 flox/flox mice were crossed with Zp3-Cre transgenic mice carrying cre-recombinase under the control of the oocyte-specific Zp3 promoter 26 to generate … " - Mouse srsf3

Mouse srsf3

Deletion of serine/arginine‐rich splicing factor 3 in hepatocytes ...

Nettet21. mar. 2024 · RASSF3 (Ras Association Domain Family Member 3) is a Protein Coding gene. Diseases associated with RASSF3 include Growth Hormone Secreting Pituitary … Nettet23. jun. 2024 · IgG was used as a negative control. e Co-immunofluorescence staining of PTBP2 (left panels) and SRSF3 (right panels) with hnRNPH1 in adult mouse testes. P pachytene spermatocytes, RS round...

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NettetSRSF3 is phosphorylated at AKT consensus sites downstream of PI3K‑mediated platelet‑derived growth factor receptor α signaling in mouse palatal mesenchymal cells, resulting in its nuclear translocation (56). However, SRSF3 appears to be hypo‑phosphorylated and stable in cells(57), which may be a way to maintain cell … NettetAll lanes : Anti-SRSF3 antibody [EPR16976] (ab198291) at 1/1000 dilution Lane 1 : Mouse brain lysate Lane 2 : Rat brain lysate Lane 3 : C6 (Rat glial tumor) whole cell lysate Lane 4 : RAW 264.7(Mouse macrophage cells transformed with Abelson murine leukemia virus) whole cell lysate Lane 5 : PC-12 (Rat adrenal gland pheochromocytoma) whole cell …

Nettet31. jan. 2024 · We identified hnRNPM and SRSF3 as key factors required to suppress exon 6A inclusion and maintain high DHX9 expression in Ewing sarcoma cells. Importantly, downregulation of SRSF3 or hnRNPM sensitized Ewing sarcoma cells to doxorubicin, a genotoxic agent used in Ewing sarcoma chemotherapy. NettetUse Bio-Rad's PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed.

Nettet26. okt. 2016 · We confirmed this observation, both on an mRNA and protein level, by comparing soleus with the gastrocnemius and quadriceps from our transgenic ISCU mice. SRSF3 is the smallest member of the conserved SR protein family and consists of an N-terminal RNA binding domain and a C-terminal domain rich in arginine and serine [24, … Nettet12. nov. 2024 · It has been reported that SRSF3 may facilitate reprogramming from mouse embryonic fibroblasts (MEFs) and maintain the pluripotency status of mouse induced …

Nettet9. mai 2024 · We establish serine-arginine-rich splicing factor 3 (SRSF3) as an essential regulator of RNAs encoding key components of the mouse pluripotency circuitry, …

Nettet25. sep. 2024 · Ser/Arg-rich splicing factor 3 (SRSF3) is the smallest member of the SR protein family, and its level is controlled by multiple factors and involves complex … scph yahoo finance scph tickerNettet1. aug. 2024 · SRSF3, the smallest of the SR proteins, was first identified and cloned by Zahler et al. (1992). It plays an essential role in early vertebrate development as SRSF3-null mouse embryos fail to form blastocysts and die … scph ps2http://www.informatics.jax.org/marker/MGI:3649769 scph summit countyNettet16. aug. 2004 · P84104 · SRSF3_MOUSE. Protein. Serine/arginine-rich splicing factor 3. Gene. Srsf3. Status. UniProtKB reviewed (Swiss-Prot) Organism. Mus musculus (Mouse) Amino acids. 164. ... a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements … scph toolkitNettet23. jun. 2024 · e–f Co-immunofluorescence staining of PTBP2 (e) and SRSF3 (f) with SYCP3 in testis sections from adult control and hnRNPH1 cKO mice. The DNA was … scph-10020Nettet17. aug. 2016 · Serine rich splicing factor 3 (SRSF3) ... Mice lacking peroxisome-proliferator activated receptor-γ (PPARγ) in neurons do not … scph-1000