Ctbp ogdhl

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August undefined, 2024

WebAug 5, 2024 · Gene ID: 55753, updated on 5-Aug-2024 Summary The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. WebAug 14, 2015 · The OGDHL promoter methylation pattern was assumed to provide a marker for differential diagnosis of CIMP+ (CpG island methylator phenotype) tumors, which display dense hypermethylation of the promoter region in many genes. Cell metabolic reprogramming is one of the cancer hallmarks. Glycolysis activation, along with …

OGDHL Is a Modifier of AKT-Dependent Signaling and NF- B …

WebJan 12, 2024 · OGDHL is predicted to be a thiamine diphosphate-dependent 2-oxo acid dehydrogenase ( EC 1.2.4.2) for reduction of protein-bound lipoyl groups ( Bunik and Degtyarev, 2008 ). OGDHL encodes a rate-limiting enzyme in the Krebs cycle that plays a pivotal role in mitochondrial metabolism ( Yap et al., 2024 ). Cloning and Expression iphone 13 see notifications

Tissue expression of OGDHL - Summary - The Human Protein Atlas

WebThe CtBP1 protein was originally identified as a human protein that bound a PLDLS motif in the C-terminus of adenovirus E1A proteins. It and the related protein CTBP2 were later shown to function as transcriptional corepressors. [7] That is, regulatory proteins that bind to sequence-specific DNA-binding proteins and help turn genes off. WebJan 14, 2024 · In a 15-year-old girl (BAB4852), born of consanguineous Turkish parents, with Yoon-Bellen neurodevelopmental syndrome (YOBELN; 619701), Yoon et al. (2024) identified a homozygous c.2333C-T transition (c.2333C-T, NM_018245) in exon 18 of the OGDHL gene, resulting in a ser778-to-leu (S778L) substitution at a conserved region in … WebJul 22, 2024 · Hepatocyte-specific SIRT5 overexpressing mice (liver SIRT5 OE) were generated to address the possible involvement of hepatic SIRT5 in AMI. The areas of myocardial infarction, myocardial fibrosis, and cardiac function in a model of experimental myocardial infarction were compared between liver SIRT5 OE mice and wild-type (WT) … iphone 13 sharp edges

The Potential of Metabolism-Related Gene OGDHL as a …

OGDHL silencing promotes hepatocellular carcinoma by …

WebFeb 25, 2024 · In a 15-year-old girl (BAB4852), born of consanguineous Turkish parents, with Yoon-Bellen neurodevelopmental syndrome (YOBELN; 619701), Yoon et al. (2024) identified a homozygous c.2333C-T transition (c.2333C-T, NM_018245) in exon 18 of the OGDHL gene, resulting in a ser778-to-leu (S778L) substitution at a conserved region in … Web3PL Freight & Shipping Solutions. Coastal Transportation Services Commitment to Excellence means that we deliver personalized service at competitive prices with one … iphone 13 sfrThe CtBP1 protein was originally identified as a human protein that bound a PLDLS motif in the C-terminus of adenovirus E1A proteins. It and the related protein CTBP2 were later shown to function as transcriptional corepressors. That is, regulatory proteins that bind to sequence-specific DNA-binding proteins and help turn genes off. CtBPs do this by recruiting histone modifying enzymes that add repressive histone marks and remove activating marks. CtBP proteins can also self-as… iphone 13 sfr prix

"WebTissue proteome. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. OGDHL. " - Ctbp ogdhl

Ctbp ogdhl

Exclusive neuronal detection of KGDHC-specific subunits in

WebOGDHL (FLJ10851) protein expression summary. The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glu cose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. WebAug 5, 2024 · OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism. OGDHL closely associates with tumor microenvironment and can …

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WebMay 31, 2024 · Scientists found that osteopontin is a bad player. It also supports a “good actor” role for an enzyme called 2-Oxoglutarate Dehydrogenase-Like or OGDHL. In the presence of elevated levels of osteopontin, however, OGDHL becomes dysregulated. WebOGDHL has 3,312 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 66 datasets. Click the + buttons to view associations for ...

WebConclusion: Our findings established that silencing of OGDHL contributed to HCC development and survival by regulating glutamine metabolic pathways. OGDHL is a … WebImmunohistochemistry of paraffin-embedded human brain using 17110-1-AP (OGDHL antibody) at dilution of 1:100 (under 10x lens). Mouse kidney tissue were subjected to …

WebNov 13, 2007 · The OGDHC complex comprises multiple copies of three catalytic enzyme components, the 2-oxoglutarate dehydrogenase (OGDH/E1), the dihydrolipoamide … WebKnockdown of OGDHL expression in cervical cancer cells expressing endogenous OGDHL had the opposite effect. Forced expression of OGDHL increased the production of …

WebJan 25, 2024 · The ketoglutarate dehydrogenase complex (KGDHC) consists of three different subunits encoded by OGDH (or OGDHL), DLST, and DLD, combined in different stoichiometries. DLD subunit is shared between KGDHC and pyruvate dehydrogenase complex, branched-chain alpha-keto acid dehydrogenase complex, and the glycine …

WebApr 7, 2024 · Furthermore, the higher OGDHL protein expression except the change of PLA2G2 was also found in DCM hearts, and its mRNA expression was negatively … iphone 13 selfie stickWebJul 31, 2024 · ogdhl沉默后，以αkg依赖性方式激活了mtorc1信号通路，从而诱导了在新生脂肪形成中具有关键作用的酶发生转录，进一步说明了ogdhl的功能。前面的功能实验 … iphone 13 setup new phoneWebAug 5, 2024 · OGDHL oxoglutarate dehydrogenase L Gene ID: 55753, updated on 5-Aug-2024 Gene type: protein coding Also known as: YOBELN See all available tests in GTR for this gene Go to complete Gene record for OGDHL Go to Variation Viewer for OGDHL variants Summary iphone 13 series battery lifeWebApr 9, 2024 · CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor; NM_001377187.1 → NP_001364116.1 C-terminal-binding protein 1 isoform 4. Status: REVIEWED. Source sequence(s) AC092535 Consensus CDS CCDS93461.1 UniProtKB/TrEMBL H0Y8U5 Conserved Domains (1) summary … iphone 13 sfr black fridayWebThe overexpression of OGDHL also markedly suppressed the growth of HCC-LM3/OGDHL xenograft tumors in immunodeficient mice (p = 0.014; Figure 8C,D); these findings were … iphone 13 shield caseWebOct 17, 2024 · Background and Objective . Liver cancer is a highly malignant tumor, and patients typically have poor prognoses. Metabolic reprogramming is a hallmark of cancer, and downregulation of … iphone 13 shattered backWebPaperwork Reduction Act Notice: An agency may not conduct or sponsor an information collection and a person is not required to respond to this information request unless it … iphone 13 shipment